The Siteman Cancer Center at Washington University is the recipient of two, multi-million dollar grants awarded by the National Cancer Institute. The grants total $26-million and will help establish the School of Medicine as a premier center for innovative leukemia research.
Doctors hope the research will lead to more personalized treatments for patients based on the unique makeup of their leukemia cells. They also hope to discover therapies that improve survival and reduce treatment-related side effects.
In addition, the grant funding will enable the Center to capitalize on research advances at the medical school in order to bring new investigational treatments into clinical trials.
ST. LOUIS (AP) -- David Backes had a goal and assist in the first period to lead the St. Louis Blues to a 4-2 win over the Nashville Predators on Thursday in the season opener for both teams.
The Blues scored three times in the first 9:45 to jump in front 3-0 and chase Nashville goalie Pekka Rinne.
Jaroslav Halak made 28 saves for the Blues and improved to 9-3-3 against the Predators.
Backes, Vladimir Sobotka, T.J. Oshie and Alex Steen scored for St. Louis, which was 2 of 4 on the power play.
St. Louis has won four of its past five home openers.
Nashville, which missed the playoffs last season, is 7-7-1 in season openers.
Backes scored from close range at 2:05, just three seconds after Matt Cullen was sent off for tripping. Backes pounced on a shot from the blue line by Alex Pietrangelo, who added two first-period assists.
Sobotka tallied on a break along the left wing to make it 2-0. He went by Kevin Klein and sent a backhand behind Rinne.
Oshie converted on a pass from Steen to push the lead to 3-0. Rinne was pulled after giving up three goals on six shots.
Nashville climbed within 3-2 on goals by Mike Fisher and David Legwand.
Steen scored a power-play goal at 11:16 of the second period to stretch the lead to 4-2.
NOTES: The game began at 7:48 p.m. local time, 43 minutes after the final out of the Cardinals' 9-1 win over Pittsburgh in the opening game of the NL Division Series. The Blues moved the start time back 30 minutes to allow fans to make the five-block trip from Busch Stadium. ... St. Louis has made the playoffs in 37 of its 46 seasons. ... Nashville coach Barry Trotz is the longest-tenured head coach with the same team with 1,115 games. ... St. Louis LW Brenden Morrow fixed his work-visa problems earlier in the day and was able to play. ... Blues coach Ken Hitchcock improved to 10-3-4 in season openers. ... Nashville defenseman Seth Jones, the No. 4 overall pick in last year's draft, made his debut. He is the son of former NBA journeyman Popeye Jones.
ST. LOUIS (AP) -- Carlos Beltran, Adam Wainwright and the St. Louis Cardinals gave Pittsburgh a quick reality jolt.
Beltran's three-run homer sparked a seven-run third inning Thursday and the Cardinals got seven stingy innings from Wainwright to open their NL division series with a 9-1 rout of the Pirates.
"To be able to get out on a good first step and play well today I think is big for our guys confidence-wise," St. Louis manager Mike Matheny said. "Gives us an opportunity to just take some momentum, and momentum is big right now when you talk about a five-game series."
The first eight Cardinals reached safely in the third to chase A.J. Burnett, saddling the right-hander with the second-shortest outing of his career and putting Game 1 out of reach early.
A sellout crowd roared and then settled in for an easy victory by the NL Central champions, making their third consecutive trip to the postseason.
"Game 164 was rough," Pirates manager Clint Hurdle said. "One of the things we've been good at is we don't overcook things."
Lance Lynn (15-10) faces Pittsburgh rookie Gerrit Cole (10-7) in Game 2 on Friday.
After a record 20 straight losing seasons, the Pirates are back in the playoffs for the first time since 1992. They entered their first best-of-five division series with plenty of momentum after beating Cincinnati in the wild-card game Tuesday, but Pittsburgh never threatened to rally against Wainwright and finished with only four hits.
Pittsburgh also was sloppy in the field, committing three errors. St. Louis was sharp on defense, with reliever Carlos Martinez turning in the top play by slinging an off-balance throw to first to nip Russell Martin in the eighth.
"What a play!" Matheny mouthed in the dugout.
Third baseman David Freese prevented extra bases in the third with a diving catch on Clint Barmes' low liner.
Wainwright remained unbeaten in the postseason, going to 3-0 with a 2.27 ERA in 14 games, five of them starts.
He allowed a run on three hits in seven innings, striking out nine without a walk. The only damage came on a homer by Pedro Alvarez to start the fifth.
The right-hander tied for the NL lead with 19 wins this year and was 4-0 in his last five starts. He thrives on expectations.
"I'd love to be that guy," Wainwright said. "It's important to have somebody go out there that you can count on for sure."
Wainwright also started the Cardinals' big burst with a leadoff, full-count walk.
Beltran, who has never reached the World Series, reprised his role as one of the game's greatest playoff sluggers. His 443-foot drive to the distant second deck in right field put St. Louis ahead and was the second-longest shot by a left-handed batter at 8-year-old Busch Stadium.
"I almost got caught up in the moment," said Wainwright, who had a perfect view from second base. "I threw my hands up in the air as soon as he hit it, I knew it was gone.
"Then I realized I had to run."
Beltran has 15 home runs, 10 doubles and 28 RBIs in 35 postseason games. He also has scored 40 runs and stolen 11 bases.
Leadoff man Matt Carpenter called Beltran "Mr. October."
"He's like our secret weapon when it comes to the postseason. He steps up every time," Carpenter said. "Some guys just have a knack for a big game and he's one of them."
Beltran's 13 career RBIs against Burnett are the most of any player.
Beltran's homer got the Cardinals going, and Jon Jay later walked with the bases loaded. Freese added a two-run single that cleared the bases when right fielder Marlon Byrd's throw to the plate deflected off Freese's leg for an error.
Burnett was 3-1 against the Cardinals this season but has gotten rocked in his last two visits to St. Louis, also giving up five runs in three innings in early September. In five outings at Busch Stadium the last two seasons he has a 15.50 ERA.
"Hopefully, we can turn it around and give me a chance to get that ball again," Burnett said. "I was not able to repeat a single delivery all day, that's the bottom line."
Hurdle was non-committal on whether Burnett would get the ball if the Pirates make it to Game 5, again in St. Louis.
"I do believe that he's capable of going out and throwing a gem the next time he's out there, wherever that may be," Hurdle said.
While the Pirates may have had trouble at the plate and in the field with the shadows, the late-afternoon start didn't seem to bother the Cardinals.
"Everybody was seeing the ball good today," rookie Matt Adams said.
NOTES: Cardinals broadcaster Mike Shannon threw the first pitch in the dirt, with reserve Shane Robinson making a nice scoop. ... St. Louis OF Matt Holliday walked and doubled his first two trips and had reached base safely in nine straight plate appearances before grounding out to start the fourth. ... The Cardinals claimed OF Joey Butler on waivers, three days after he was designated for assignment by the Rangers. Butler spent most of the year at Triple-A Round Rock, batting .291 with 12 homers and 51 RBIs.