Click for St. Louis, Missouri Forecast

// a href = ./ // St Louis News, Weather, Sports, The Big 550 AM, St Louis Traffic, Breaking News in St Louis

Online pharmacy:fesmag.com/tem

Have you a sex problem? Please visit our site:fesmag.com/medic

Site map
 
 
 
Thursday, 31 October 2013 02:17

HIV-like virus suppressed in monkey experiment

   NEW YORK (AP) — Doctors may one day be able to control a patient's HIV infection in a new way: injecting swarms of germ-fighting antibodies, two new studies suggest.

   In monkeys, that strategy sharply reduced blood levels of a cousin of HIV. The results also gave tantalizing hints that someday the tactic might help destroy the AIDS virus in its hiding places in the body, something current drugs cannot do.

   The study results "could revolutionize efforts to cure HIV" if the approach is found to work in people, said a commentary published Wednesday by the journal Nature along with the monkey studies.

   Antibodies are proteins in the blood that grab onto specific germs and mark them for elimination. People infected with HIV naturally make antibodies to fight the AIDS virus, but they are generally ineffective. The two new studies used lab-made versions of rare antibodies with unusual potency against HIV.

   One study of rhesus monkeys showed a profound effect from a single injection of antibodies, said lead author Dr. Dan Barouch of Harvard and the Beth Israel Deaconess Medical Center in Boston.

   The 18 animals had been infected with SHIV, a monkey version of HIV. In 13 animals, blood levels of SHIV became undetectable by standard tests within a week of the treatment. After the antibodies petered out, the virus came back. That happened one to three months after treatment.

   In three monkeys with the lowest levels of SHIV before treatment, the virus didn't return during an observation period of up to eight months. Barouch said the animals were not cured, but the treatment had apparently improved their immune systems enough to keep the virus in check.

   The two other monkeys started with the highest blood levels of SHIV. Treatment lowered those levels but not to the point where they were undetectable.

   The second study in Nature, from the National Institutes of Health, showed encouraging results in a smaller group of monkeys.

   In people, standard drugs routinely tamp down HIV to undetectable levels in the blood. But the antibody approach may someday help doctors attack virus that's hiding in infected cells, beyond the reach of today's drugs, said the Nature commentary by Dr. Steven Deeks of the University of California, San Francisco, and Dr. Louis Picker of the Oregon Health & Science University in Beaverton.

   In theory, antibodies might activate the body's immune system to kill those infected cells, they wrote. Barouch's results hinted at such an effect, they noted. Virus levels dropped faster in the monkeys than they do when people get standard HIV drugs, and when the monkey virus returned, it generally didn't reach its pre-treatment levels. Barouch also found virus levels reduced in cells and tissues after treatment.

   The findings of the two studies are "provocative" about prospects for attacking HIV's hiding places, Deeks said in a telephone interview.

   "These studies raised more questions than they answered," he said. "But that's how science advances."

   ___

   Online:  Nature: http://www.nature.com/nature

Published in Health & Fitness

   CHICAGO (AP) - A pair of new Illinois laws will fund diabetes research and track economic costs of the disease.

   Gov. Pat Quinn signed the bills Thursday at a conference organized by the University of Chicago Medicine's Kovler Diabetes Center.

   One measure creates a special license plate. Just over half of the $40 cost of the plate will go to the Diabetes Research Checkoff Fund.

   House minority leader Tom Cross sponsored the bill. He hopes the license plate will serve as a "moving billboard" for diabetes awareness.

   The second bill requires the Illinois State Diabetes Commission to report regularly on the economic and social costs of diabetes and efforts to prevent the disease.

   The laws take effect Jan. 1.

   The Illinois Department of Public Health says about 800,000 state residents have diabetes.

 
Published in Health & Fitness

Latest News

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
Prev Next
St. Louis priest accused of having sex with minor

St. Louis priest accused of having sex with minor

St. Louis, MO (KTRS) - A St. Louis priest is accused of having sex with a minor at the Cathedral Basilica, where he served.   Reverend Joseph Jiang was arrested on ...

Missouri man in custody after clerical error frees him from prison

Missouri man in custody after clerical error frees him …

ST. LOUIS (AP) - A Missouri man who avoided prison because of a clerical error and led a law-abiding life for 13 years said he is overwhelmed by the support he's received since ...

Hazelwood voters could vote on new utility tax

Hazelwood voters could vote on new utility tax

St. Louis, MO (KTRS) - Hazelwood residents could soon have the chance to vote on a proposed utility tax.   Currently, Hazelwood is the only St. Louis County municip...

Courts moving away from eyewitness testimony as gold standard

Courts moving away from eyewitness testimony as gold st…

PORTLAND, Ore. (AP) - Courts and legislatures are slowly shifting away from using eyewitness testimony as the gold standard of evidence. The reason: Studies show it's only right...

One Cent Sales Tax For Transportation Endorsed

JEFFERSON CITY, Mo. (AP) - A Missouri Senate committee has endorsed a 1-cent sales tax increase to fund transportation projects.     The proposed constitutiona...

Safe Rooms Opening Soon In Joplin

(Joplin, MO)  --  Joplin officials say some safe rooms to protect residents during storms are expected to open in the next few weeks. Joplin school officials say f...

Dog Shooting Investigated In Washington, MO

WASHINGTON, Mo. (AP) - An investigation continues after an eastern Missouri deputy shot and killed a dog. The Washington Missourian reports that Franklin County deputies wen...

© 2013 KTRS All Rights Reserved