Click for St. Louis, Missouri Forecast

// a href = ./ // St Louis News, Weather, Sports, The Big 550 AM, St Louis Traffic, Breaking News in St Louis

Online pharmacy:fesmag.com/tem

Have you a sex problem? Please visit our site:fesmag.com/medic

 
 
 
KTRS News

KTRS News

HALF OF US ADULTS 40 TO 75 ELIGIBLE FOR STATINS

Thursday, 20 March 2014 06:10 Published in Health & Fitness

Almost half of Americans ages 40 to 75 and nearly all men over 60 qualify to consider cholesterol-lowering statin drugs under new heart disease prevention guidelines, an analysis concludes.

It's the first independent look at the impact of the guidelines issued in November and shows how dramatically they shift more people toward treatment. Supporters say they reveal the true scope of heart risks in America. Critics have said the guidelines overreach by suggesting medications such as Zocor and Lipitor for such a broad swath of the population.

"We wanted to be really objective and just quantify what the guidelines do, and not get into a discussion about whether they are correct," said Michael Pencina, the Duke University biostatistician who led the analysis. It was published online Wednesday by the New England Journal of Medicine.

Under the new guidelines, 56 million Americans ages 40 to 75 are eligible to consider a statin; 43 million were under the old advice. Both numbers include 25 million people taking statins now.

"That is striking ... eye-opening," Dr. Daniel Rader of the University of Pennsylvania said of the new estimate.

But since too few people use statins now, the advice "has the potential to do much more good than harm," said Rader, a cardiologist who had no role in writing the guidelines.

Nearly half a million additional heart attacks and strokes could be prevented over 10 years if statin use was expanded as the guidelines recommend, the study estimates.

The guidelines, developed by the American Heart Association and American College of Cardiology at the request of the federal government, were a big change. They give a new formula for estimating risk that includes blood pressure, smoking status and many factors besides the level of LDL or "bad" cholesterol, the main focus in the past.

For the first time, the guidelines are personalized for men and women and blacks and whites, and they take aim at strokes, not just heart attacks. Partly because of that, they set a lower threshold for using statins to reduce risk.

The guidelines say statins do the most good for people who already have heart disease, those with very high LDL of 190 or more, and people over 40 with Type 2 diabetes.

They also recommend considering statins for anyone 40 to 75 who has an estimated 10-year risk of heart disease of 7.5 percent or higher, based on the new formula. (This means that for every 100 people with a similar risk profile, seven or eight would have a heart attack or stroke within 10 years.)

Under this more nuanced approach, many people who previously would not have qualified for a statin based on LDL alone now would, while others with a somewhat high LDL but no other heart risk factors would not.

The Duke researchers gauged the impact of these changes by using cholesterol, weight and other measurements from health surveys by the Centers for Disease Control and Prevention. They looked at how nearly 4,000 people in these surveys would have been classified under the new and old guidelines, and projected the results to the whole country.

The biggest effect was on people 60 and older, researchers found. Under the new guidelines, 87 percent of such men not already taking a statin are eligible to consider one; only 30 percent were under the old guidelines. For women, the numbers are 54 percent and 21 percent, respectively.

Dr. Paul Ridker and Nancy Cook of Brigham and Women's Hospital in Boston have criticized the risk formula in the guidelines. Ridker declined to be interviewed, but in a statement, he and Cook noted that most people newly suggested for statins do not have high cholesterol but smoke or have high blood pressure. Those problems and lifestyle changes should be addressed before trying medications - which the guidelines recommend - they write.

Dr. Neil Stone, the Northwestern University doctor who helped lead the guidelines work, stressed that the guidelines just say who should consider a statin, and they recommend people discuss that carefully with a doctor.

"We think we're focusing the attention for statins on those who would benefit the most," Stone said.

Dr. Harlan Krumholz, a Yale University cardiologist who has long advocated this approach, agreed.

"The guidelines provide a recommendation, not a mandate" for statin use, he said.

Pencina, the leader of the Duke study, said his own situation motivated him to look at the guidelines more closely. His LDL was nearing a threshold to consider a statin under the old guidelines, but under the new formula for gauging risk, "I'm fine," he said.

---

Online:

Cholesterol info: HTTP://TINYURL.COM/2DTC5VY

Risk formula: HTTP://MY.AMERICANHEART.ORG/CVRISKCALCULATOR

Heart facts: HTTP://CIRC.AHAJOURNALS.ORG/CONTENT/127/1/E6

---

Marilynn Marchione can be followed at HTTP://TWITTER.COM/MMARCHIONEAP

© 2014 THE ASSOCIATED PRESS. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED. Learn more about our PRIVACY POLICY and TERMS OF USE.

Martinez, Gibson sharp in starts

Wednesday, 19 March 2014 23:15 Published in Sports
 
JUPITER, Fla. (AP) -- St. Louis' Carlos Martinez and Minnesota's Kyle Gibson each enhanced their chances of earning a spot in their team's rotation with solid outings, and the Cardinals beat the Twins 3-1 on Wednesday.
 
Martinez cruised into the fifth, holding the Twins to one hit, but Jason Bartlett had an RBI single to right-center in the sixth that ended the right-hander's scoreless string at 14 innings.
 
For Bartlett, the hit was his first of the spring in 27 at-bats.
 
The 22-year-old righty struck out four but kept his pitch count low by inducing two inning-ending double plays.
 
"He's starting to learn his stuff but he's also trusting a pretty good catcher behind the plate to help him understand which ones he needs to focus on and what pitches are most likely to get him out of a jam," St. Louis manager Mike Matheny said.
 
Making his fourth appearance - second start - Gibson limited the Cardinals to Matt Adams' second homer of spring training in 4 1-3 innings. Gibson allowed four hits.
 
"He's pitching really well," Minnesota manager Ron Gardenhire said. "We really like him. He's doing what he's supposed to do. That's good stuff."
 
Peter Bourjos doubled and scored the go-ahead run on a wild pitch by Samuel Deduno in the eighth inning.
 
STARTING TIME
 
Minnesota: Deduno is also a candidate for the fifth spot in the Twins' rotation. Deduno had allowed one earned run in 9 2-3 innings. He piggybacked Gibson against the Cardinals, allowing two runs in 2 2-3 innings.
 
St. Louis: As good as Martinez was in short relief last season, one reason the Cardinals believe he will eventually be a starter is that in minor league starts his fastball didn't lose much of its velocity over the course of multiple innings.
 
"There are some guys who can come out and just really light up the (radar) gun for an inning or so. There's other guys that can hold it. He's been one that's been able to hold it," Matheny said.
 
TRAINER'S ROOM
 
Twins: shortstop Pedro Florimon made his Grapefruit League debut on Tuesday night and was back in the lineup again on Wednesday. After missing much of the spring because of an appendectomy, Florimon should be a fixture in Minnesota's lineup over the final week-and-a-half.
 
"He needs at-bats," Gardenhire said. "He needs to play because he sat out the whole spring and then we'll see where we are in a week and go from there, but I'm going to try to get him out there pretty much every day."
 
Cardinals: Second baseman Mark Ellis' sore knee continues to keep him out of action. Matheny said Ellis could play were it the regular season, but the veteran will likely get at least a couple more days off.
 
NESHEK BACK
 
Pat Neshek pitched in a major league game for the first time since leaving Cardinals camp last week to be with his wife for the birth of their child. A non-roster invitee, Neshek struck out two and earned the save on Wednesday.
 
SUPER UTILITY
 
Barlett received his first spring start at third base for the Twins. Defense hasn't been the non-roster invitee's problem. He entered Wednesday's game 0 for 24 at the plate.
 
"He's actually having quality at-bats," Gardenhire said. "The numbers in spring training never affect me if you are having quality at-bats."
 
ROSTER MOVES
 
After the game, Matheny said St. Louis sent pitcher Tyler Lyons to the minors. Early in the spring, Lyons was thought to be an option for the fifth starting spot. He worked exclusively out of the bullpen once games began, allowing 13 runs in eight innings.
 

Blackhawks beat Blues 4-0 behind Crawford

Wednesday, 19 March 2014 23:12 Published in Sports
 
CHICAGO (AP) -- Corey Crawford stopped 23 shots for his second shutout this season, backstopping the Blackhawks to a physical 4-0 victory over the St. Louis Blues on Wednesday night that gave Chicago coach Joel Quenneville his 700th NHL win.
 
It was a costly victory for the Blackhawks, though. Leading scorer Patrick Kane left the game at 7:56 of the second period, favoring his left leg as he headed to the dressing room following a collision with Brenden Morrow.
 
Kane is expected to miss about three weeks, Quenneville said.
 
Duncan Keith, Andrew Shaw, Marcus Kruger and Ben Smith scored as Chicago ended the league-leading Blues' nine-game point streak (8-0-1) and dealt St. Louis its first regulation loss against a Central Division opponent this season. The Blues entered 20-0-2 against division foes and hadn't lost in regulation since a 1-0 defeat at Anaheim on Feb. 28.
 
Quenneville, who previously guided St. Louis and Colorado, has the most wins of any active NHL coach and ranks third all-time behind Al Arbour and Scotty Bowman, now the Blackhawks' senior adviser of hockey operations.
 
Crawford earned his 10th career shutout in Chicago's first win against the Blues this season after three losses.
 
Kane, who has 29 goals and 40 assists in 68 games, assisted on Keith's opening goal.
 
St. Louis goalie Ryan Miller lost in regulation for the first time since joining the Blues following a trade from Buffalo on Feb. 28. Miller, now 7-1-1 with St. Louis, was replaced by Brian Elliott at 7:58 of the third period after allowing four goals on 27 shots.
 
St. Louis needs one win to clinch a playoff spot for the 38th time in franchise history.
 
Defending Stanley Cup champion Chicago entered the game tied with Colorado for second in the Central Division and fourth in the Western Conference.
 
The Blackhawks have struggled this season against their top rivals in the Central. Chicago entered Wednesday's game with only one win and five points in eight games against St. Louis and Colorado.
 
Keith scored the only goal in a physical first period on a power play with 58 seconds left.
 
After taking Kane's feed, Keith fired a drive from the top of the slot that zipped past Miller's stick side just as Shaw provided a screen by cutting across the crease.
 
The play got tighter and grittier in the second, and Chicago took a 2-0 lead thanks to Shaw's goal on a deflection with 4:25 left in the period.
 
Shaw's goal capped a determined, physical flurry by Chicago.
 
The Blackhawks were jamming the net when Patrick Sharp picked up a loose puck and fed back to Nick Leddy at the blue line. Leddy's drive ticked off the shaft of Shaw's stick and past Miller as Shaw battled for position in front of the net with Blues defenseman Alex Pietrangelo.
 
Blues defenseman Kevin Shattenkirk threw a loose rebound behind Crawford during a St. Louis power play in the final seconds of the second, but the puck slid across the crease and to the far boards.
 
Kruger and Smith scored 2:15 apart in the third period to ice it for Chicago.
 
Following a long lead pass from defenseman Niklas Hjalmarsson, Kruger took a quick feed from Peter Regin in the slot and beat Miller from just outside the crease at 5:20 to make it 3-0.
 
Smith's power-play goal at 7:35 extended Chicago's lead to 4-0. He connected from the doorstep after taking a feed from Kris Versteeg behind the net after Miller stopped Leddy's shot from the blue line.
 
Notes: Blackhawks C Michal Handzus played in his 1,000th NHL game and was honored in a pregame ceremony. He turned 37 last week. ... St. Louis RW Vladimir Tarasenko underwent surgery for a right hand injury sustained last Saturday at Nashville in the final minute of the game. He will be re-evaluated in six weeks. ... Blues RW T.J. Oshie returned to the lineup after missing one game for the birth of his first child. ... Chicago LW Brandon Saad sat out his second game with an upper-body injury and is day to day.

Latest News

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
Prev Next
Cards pitching shuts down Brewers again 6-1

Cards pitching shuts down Brewers again 6-1

MILWAUKEE (AP) -- Shelby Miller struck out seven and allowed three hits over six innings, and Mark Ellis had two RBIs in his return from the disabled list to lead the St. Louis ...

Lynn, Cardinals snap Brewers' 9-game win streak

Lynn, Cardinals snap Brewers' 9-game win streak

MILWAUKEE (AP) -- The Milwaukee Brewers' nine-game winning streak was snapped Monday night when Lance Lynn struck out 11 in seven innings and Jon Jay hit a three-run homer for t...

49ERS LINEBACKER ALDON SMITH ARRESTED AT AIRPORT

49ERS LINEBACKER ALDON SMITH ARRESTED AT AIRPORT

LOS ANGELES (AP) -- San Francisco 49ers linebacker Aldon Smith was arrested Sunday at Los Angeles International Airport after authorities said he became belligerent during a sec...

Red Wings keep Blues down with 3-0 shutout

Red Wings keep Blues down with 3-0 shutout

  ST. LOUIS (AP) -- Backup goalie Petr Mrazek kept the injury-riddled St. Louis Blues down heading into the playoffs with his second career shutout in a 3-0 victory for...

Carpenter, Wainwright help Cardinals top Cubs 10-4

Carpenter, Wainwright help Cardinals top Cubs 10-4

ST. LOUIS (AP) -- Matt Adams homered, Matt Carpenter drove in two runs and Adam Wainwright saved a tired bullpen by lasting seven innings for the St. Louis Cardinals in their 10...

Daley, Stars beat Blues 3-0, end playoff drought

Daley, Stars beat Blues 3-0, end playoff drought

DALLAS (AP) -- Trevor Daley had a goal and an assist, Kari Lehtonen recorded his fifth shutout of the season, and the Dallas Stars clinched their first playoff berth since 2008 ...

Curry, Wild extend Blues' slide with 4-2 win

Curry, Wild extend Blues' slide with 4-2 win

  ST. PAUL, Minn. (AP) -- Kyle Brodziak scored two goals and John Curry made 43 saves in his Wild debut to lead Minnesota over the struggling St. Louis Blues 4-2 on Thu...

© 2013 KTRS All Rights Reserved