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LONDON (AP) -- A Swedish doctor says four women who received transplanted wombs have had embryos transferred into them in an attempt to get pregnant.
He would not say on Monday whether any of the women had succeeded. In all, nine women in Sweden have received new wombs since 2012, but two had to have them removed because of complications.
The women received wombs donated by their mothers or other close relatives in an experimental procedure designed to test whether it's possible to transfer a uterus so a woman can give birth to her own biological child. The women had in vitro fertilization before the transplants, using their own eggs to make embryos.
"We have already begun transferring embryos into four of the women and plan to make attempts with the others when they are ready," said Dr. Mats Brannstrom, a professor of obstetrics and gynecology at the University of Goteburg, who is leading the research.
Brannstrom predicted that three or four of the seven women might successfully give birth.
"One or two more will perhaps get pregnant and miscarry, and one or two won't be able to get pregnant," he said.
There have been two previous attempts to transplant a womb - in Turkey and Saudi Arabia - but both failed to produce babies. Doctors in Britain and Hungary also are planning similar operations, but using wombs from women who had just died.
Brannstrom said any woman in the study who does get pregnant will be on a low dose of drugs to keep from rejecting the transplanted womb and will be monitored as a high-risk pregnancy.
The transplants are intended to benefit women unable to have children because they lost a uterus to cancer or were born without one.
Some doctors said women who got pregnant with a new uterus would have to be watched carefully for how the womb progresses throughout pregnancy.
"There are questions about how the physiological changes in the uterus will affect the mother and whether the transplanted uterus will be conducive to a growing baby," said Dr. Charles Kingsland, a spokesman for Britain's Royal College of Obstetricians and Gynaecologists and a gynecologist at Liverpool Women's Hospital.
In a study published last week, Brannstrom and colleagues described the procedures used to transplant the nine wombs and said there were "mild rejection episodes" in four patients.
He said the transplanted wombs would be removed after a maximum of two pregnancies.
Other experts called it a promising step but said it would be crucial that babies get enough nutrients from the mother's blood supply.
"We really don't know if the blood flow to the uterus will increase and adapt in the same way," as in a regular pregnancy, said Dr. Yacoub Khalaf, director of the Assisted Conception unit at Guy's and St. Thomas' hospital in London.
"It is a good sign they have done the (embryo) transfers," Khalaf said. "But a live birth will be the best validation that this works."
WASHINGTON (AP) -- Sick of hearing about the health care law?
Plenty of people have tuned out after all the political jabber and website woes.
But now is the time to tune back in, before it's too late.
The big deadline is coming March 31.
By that day, for the first time, nearly everyone in the United States is required to be signed up for health insurance or risk paying a fine.
Here's what you need to know about this month's open enrollment countdown:
ALREADY COVERED? NO WORRIES
Most people don't need to do anything. Even before the health care law passed in 2010, more than 8 out of 10 U.S. residents had coverage, usually through their workplace plans or the government's Medicare or Medicaid programs. Some have private policies that meet the law's requirements.
If you're already covered that way, you meet the law's requirements.
Since October, about 4 million people have signed up for private plans through the new state and federal marketplaces, the Obama administration says, although it's not clear how many were already insured elsewhere. In addition, many poor adults now have Medicaid coverage for the first time through expansions of the program in about half the states.
President Barack Obama is urging people who have coverage to help any uninsured friends and relatives get signed up.
NEED COVERAGE? IT'S CRUNCH TIME
Chances are you'll hear more reminders about health care this month. The push is on to reach millions of uninsured people.
The administration, insurers, medical associations and nonprofit groups are teaming up with volunteers to get the word out and guide people through the sometimes-rocky enrollment process. They plan special events at colleges, libraries, churches and work sites.
Singing cats, dogs, parrots - even a goldfish - are promoting the message in TV and online spots from the Ad Council.
A big hurdle for the effort: As recently as last month, three-fourths of the uninsured didn't know there was a March 31 deadline, according to polling conducted for the Kaiser Family Foundation. Most said they didn't know much about the law and had an unfavorable opinion of it.
Plus, many worry they won't be able to afford the new plans.
The enrollment campaign is emphasizing that subsidies are available on a sliding scale to help low-income and middle-class households pay for their insurance.
How to enroll? Start at HealthCare.gov or by calling 1-800-318-2596. Residents of states running their own marketplaces will be directed there; people in other states go through the federal exchange.
After March 31, many people won't be able to get subsidized coverage this year, even if they become seriously ill.
The next open enrollment period is set to begin Nov. 15, for coverage in 2015.
There are exceptions. The big one is the Medicaid program for the poor. People who meet the requirements can sign up anytime, with no deadline.
Also, people remain eligible for Medicare whenever they turn 65.
If you are insured now and lose your coverage during the year, by getting laid off from your job, for example, you can use an exchange to find a new policy then. People can sign up outside the open enrollment period in special situations such as having a baby or moving to another state.
You can choose to buy insurance outside the marketplaces and still benefit from consumer protections in the law.
People who do that wouldn't normally be eligible for premium subsidies. But the Obama administration says exceptions will be made for people whose attempts to buy marketplace insurance on time were stymied by continuing problems with some enrollment websites.
MILLIONS OF PEOPLE WON'T GET COVERED
Some 12 million people could gain health coverage this year because of the law, if congressional auditors' predictions don't prove overly optimistic.
Even so, tens of millions still would go without.
That's partly because of immigrants in the country illegally; they aren't eligible for marketplace policies.
Some of the uninsured will not find out about the program in time, will find it confusing or too costly, or will just procrastinate too long. Some feel confident of their health and prefer to risk going uninsured instead of paying premiums. Others are philosophically opposed to participating.
Figuring out just how many of the uninsured got coverage this year won't be easy because the numbers are fuzzy.
The administration's enrollment count includes people who already were insured and used the exchanges to find a better deal, or switched from private insurance to Medicaid, or already qualified for Medicaid before the changes.
Some who sign up will end up uninsured anyway, if they fail to pay their premiums.
The budget experts predict enrollment will grow in future years and by 2017 some 92 percent of legal residents too young for Medicare will have insurance.
But even then, about 30 million people in the United States would go uncovered.
SOME ARE LEFT OUT
A gap in the law means some low-income workers can't get help.
The insurance marketplaces weren't designed to serve people whose low incomes qualify them for expanded Medicaid instead. But some states have declined to expand their Medicaid programs. That means that in those states, many poor people will get left out.
People who fall into the gap won't be penalized for failing to get covered.
Some others are exempt from the insurance mandate, too: American Indians, those with religious objections, prisoners, immigrants in the country illegally, and people considered too poor to buy coverage even with financial assistance.
THE IRS IS WATCHING YOU
The law says people who aren't covered in 2014 are liable for a fine. That amounts to $95 per uninsured person or approximately 1 percent of income, whichever is higher. The penalty goes up in later years.
A year from now, the Internal Revenue Service will be asking taxpayers filing their forms for proof of insurance coverage. Insurance companies are supposed to provide that documentation to their customers.
If you owe a penalty for being uninsured, the IRS can withhold it from your refund.
The agency can't put people in jail or garnishee wages to get the money. But it can withhold the penalty from a future year's tax refund.
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